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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dc687bd5e593e5b1a329bdd8b46438d453d56938b7c96ed75e15903f0d7e200' 
  AND token = 'PFv6BlTAvVO/5PXaP1EB6poVyVEB2uwDIPannL6M2lQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}