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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81a9ea6b07a0549335804658c2fa758c4265c661fb58f1869f25b08ac346e63e' 
  AND token = 'vKPYe3xwY0TdWDMJ+1PBuOIJvXxEbdU+JvdnIMQ3OOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00093

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}