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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49217ff741d558294dc0a9116f15fbb644f407df47ee2e0094092a7dd6e55da4' 
  AND token = 'L57zVuB4DL7yoHddvU8NoG2YCZJIJcwN7feglyDT2eE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}