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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f88cc888a23dc35197463a776e1a7f7fc152979cf7e1cce970887040e3ea77f7' 
  AND token = 'vU4iPK8w/KHXQ5hBRdGnq4TlHIMaRdy1OlZPTjL3GL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}