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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e10b222fde6258b1eb869cd62ebed7b8fc02856b126a8d6403d1260d21a8392b' 
  AND token = 'xA0mOT520FJtEFVTPHnFSYXjY1r7dUVIHbpGcf9dEPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00083

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}