SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03039b89454f23f9301e9cb0191fd3e2adcf187f63f1b4fd2db473c07bfef3f7' 
  AND token = 'L3ESN0M/DYKn2TVFy8jsmcnuuiOPcEEW5X0YWRA6Mtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}