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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7503c09f2752e412880b5d1ce53f1ad5c7da558b2183f8225343b1abe4b8c06d' 
  AND token = 'kcoqHdu9+0B2yFjBNoJkUIiIQ2wOhTCuE0umTaVLWRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}