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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e2c32f121e59b14bba58cdddcf5b848a3eeab00601fe6d104bdb047280ae5ab' 
  AND token = 'JYwB+Kbz2OrK5L06RHmPXfHn5D0KBOljN/JOZE+SDG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}