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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd8a3efa2ea7eceb5e27277eed7dfc4d2103dd37980390d519fddba25c049538' 
  AND token = 'FQJsW865gF4WZ4pBwrWO6GDeC4OMq/oSrCGaTK45YsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}