SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c83b08a6595aea59183a9a65899b358179a98958dc421ea10eb22d5985982bfb' 
  AND token = 'DDFEtEmiaxYxs6gcqmsDqOZZBwLS1FZddF5lMTfheS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}