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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0193265f543e02dbf344c63e2aa1049e0b7873d4cbe7b9afeef24de02071b1df' 
  AND token = 'tixwHH0DQvpll3zaGUPvWFDGwJ1O48hNn4P93BJqsaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}