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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '522910ff1c503b2aa49ada97da46554f386f8c917e2c381e752fc354009473ee' 
  AND token = 'zDS7eTKsnEa3pvoFnCDAvGQlqgntyaRfEfg7os6bi38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}