SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de2c813c90954733288a1fcf060881e606354cce6fc3f9c15ed29246b85016dc' 
  AND token = 'cDBePxbZPNsNK8FA9SiVjwGxqUiq0PvmTTNb5vPUzco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}