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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9785648d2d8d8315a879a4817e23daa40ebb18cc5cec544841ed407b42d55f31' 
  AND token = 'PdOfm/HBe+vSkvIZ+dv3Ng4+wW9FGyspEWuWiHrMfrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}