SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e2904c5c698080768a42cec79688bddf69c2bb380d00f4db5d1c2cccbafca51' 
  AND token = 'zlw7NrGVjowI/ntVj5Bvdluw0WkFJNaWJf7kjIIBIbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}