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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5c566f61550bc6ee5c9b43b2ae5657d32c3fd495f1df8268d5d53bf2f694782' 
  AND token = 'Dloj8fVtREs7meB7ZaU+qe7Kigg9jpwfxCNUXtgPT6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}