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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bf2767028efacfb5450230d18bb1581b301d236b20061f40b3fa411b47388bd' 
  AND token = 's0Qg4i1+nA/uS3vsFdKwwL56hB+ZM+ewV83Y8nqOQVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}