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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41a16640f02391ef51db5c92cd3e585f2b9fca4be4256c56b88db89f3336e61c' 
  AND token = '8qFEi8uOkk1EghtccnlDXYiaUh4U2znpKntbRtwUAlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}