SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff2e8c791d8b3edfaf4bdbac44199c3a33e8538415d6d351eb707b844b79dde3' 
  AND token = 'enSmfLTFYT1jjzXSTRZ54cnm5eNLa1xi+hMCAOhJz9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}