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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f8f7e7fe655e4cb92273419a02b54b49fe49cef32e6f91e5cf99c2db9c2ac46' 
  AND token = 'HegZI8u2On+ny1Am/xTp375FY6YJe0rGUDgQe2wKUFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00081

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}