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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37ed876a2d5f6ad8354fe8c16ed12db07ccdeb46188905dc95bd2297209ae73f' 
  AND token = 'm9NIpYgiHMmu65/ZN3+iYDFFMH7B0ft4Bk08F1v1Wew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}