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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59308fd4808ae42598a50662907fa706d378ea0a47d3a2a8c28d3a617a0997f8' 
  AND token = '60hhQgzEVXYqsOFECdEGWDwxz20hP8vTRpY7uMSCZcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}