SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00af8100955247df7bed5e4afff11e06733ff95f24819aecc248122c784f7c9c' 
  AND token = 'UB4UEIU6MNYdkPEUQ3sCbk/TzjqJP+vRibs/pnGzeGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}