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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e766510352ee0691d1a7e76d99521191e46de51bc669513b06b87759702da461' 
  AND token = 'UVwH7TT2m3Si9dEgC7fTXgiFJQ3yqYX2PhpNBP3XYnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}