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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a180008f30378bd9fd0a4e1f347a70fd186a1fa84af24e52a10a539f28d946d2' 
  AND token = 'RzriWRZybLHm+jBXvdMMXwQavr838h5S5dAg0Oev4/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}