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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a742bf184dbf697669bc6d4d3d816c49ecd6fd13c212af8892b860266bda2ff7' 
  AND token = 'J3QTTJC8b04zxQnZuWHGJyDLy+fFCkDStDfoGFjbUFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}