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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c46120e4c71690ff6863a08bdb2a1f6fa2ccb79cc4678ec86cceb3839f25d97' 
  AND token = 'LzcftLPiNeb5budoblp8On6xE5iOaZ5MXYdK9pywPKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}