SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6998a1ce359614a86e5bed7eb10f86737d1b96c562e89825130c7856d95f687b' 
  AND token = '/UIh1BR8zvumCxwfKM8azS975tKdS66edTOELToz/a8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}