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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4e49e5f6989ed538e176be8c80e4a542be7b83da84c893be175d863ab6f6edd' 
  AND token = 'lqCw8bkAHonmeLvdp5qYgI94n40+ar/wmUzbJTn5UgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}