SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9345fd09597f1c9a2b5c4ef86fe223efd7d18dbc99667831062291816e89cc1d' 
  AND token = 'j6Vyn2Ubrr2+uvne+i4UKZA4YuuyHU19bqKKrll/6BI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}