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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f273428de2a55ce64bdf0f8afec744655ffc647d0a05fdfe15c8df28981474cc' 
  AND token = 'T0DSLK0y+r3F8/fbZ7MjiSbZJ8QG+jJgXnh3PIy3t08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}