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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '501e5f8b32a6734f7b3399e0238d767c119e98f4896a0290035b3090d86e6e25' 
  AND token = 't2dD5NWRgaDen/1lWxi1vKdZgPVGO6/tabAjSmI/tMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}