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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ac4975414e8ba5af29b0436b4b5722e02f222dd5bef60c9d1432e70aada2cb7' 
  AND token = 'dLCFyfZpOy0zm9KhHyWiu5mKZND5k7v5ZYRs8cRO4v8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}