SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dee8deae030e43fbcbfea1581790450ba9ae95d8094c8b384d22ecbb6a21585' 
  AND token = 'NfbQsC0s4YDRyiitODJvSUVdNUfYY/zGiwgM2PE+w0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}