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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c7e82aa1d4423820ddf34693757d7db9b78aaa85a3ae8403684f1cf8a68a881' 
  AND token = '5MxexUtzWBPMi06the2sHcXvWKUWlTQ7AFmUMEYr0iU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}