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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2a2d8554de2b27402676d1354ec58fdb6d2be317e3bd39b051cdfbd62d2dc56' 
  AND token = '4VScCYbHtasmmxY3GtkjnyMXO0PhfZCsIRFhMgVU1z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}