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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7448b387e9d7b971d98bf1dc65e087aeac0c66450e1c78df72ee630e696aba43' 
  AND token = 'qWRZihL+fBWbHrpc55sc0EBC9GEkJOIa8I9mZgaBoVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}