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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '244526c8d4bfa58fea636d0aaa4c831ceaa74e35a970a87aa8b6498dafcec16d' 
  AND token = '+FS9V6N35t3t+P2EWJ+yCS0ws3sNJAyppoTfpkiZs7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}