SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed4de54780544042d4f2c70ac1b96a925c9313fd5f76d688ae73dbfa6016b8a4' 
  AND token = 'lADsmvmUHul85tJ0Kim5Lx1+mEdQ77Ea33W8qF4hJd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}