SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ebb31bbe395354ce254b15242f69201f508feb1f9714917181b54d0acca3564' 
  AND token = 'uJlwODVKYTb78Q2TaMeRY3djtKWW2HmQsvQGP+/TSRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}