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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f2e750d426dc303b4bff8bc7531ec5d29547d290029d2cd194760d478d16c20' 
  AND token = '+dcOaFhTYsZqCW/3e/aKFd+rsXTAC26JkrV/fbULt8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}