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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f04b48e1f0029070b836a7f8c186b39af61955523b3c254960a9d5ff41f93ace' 
  AND token = 'Sz5m3by1+zZIMrzI4yWXt7y2fHK8Ctc9EWbX03gF9D0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}