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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb5b7cfd64bf5f5f0f7b6d1d11887429820867e0368f58146a983c060c778fe5' 
  AND token = 'r3Fyn6JGX5108Eq+fADIzfWSMKXh2IZH8iC3YGrG1oA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}