SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17a68978c13635518e7b9a066d705220602ea415bc009cf243080b812b68fe8c' 
  AND token = 'hIQTBEMYclaS2KJDWnTfPjPtPo2CoMpb/YSV+P6AJMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}