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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f25b5295b3565710fa26b435967891632da9b1c625add3146f9528f5d68bfb4d' 
  AND token = 'ESSyc0gRFwZ6/eMV/Mwp4ERgCRMiko6pg4VIRikP9C4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}