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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '448e384a6ac90ed51c7535572a7746de8b73df95fd3102f7b55901c588812321' 
  AND token = 'vLIZohcXigaPROmoiptVAOog1FUYDcKMtPS1jVhDnrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}