SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e6c2e37da582142ab48155b69c21da0fcc3fcbddd36efa51877f7186c41b55' 
  AND token = 'Xjx7bgcjXWtJ2Gf8sIkL6PCspxnWvzkACvHAu79PUo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}