SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a77bf90cb0839b1c1af2278c0ebaf78413da1062ed57f8c2ab88f890c120c0' 
  AND token = 'vxWG4aAE7nhdX05a78TX6eqzMK3VnZD/0Y+5JORyDmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}