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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '972cf2fdb00a20755abffe6cc34b461e257f5c575101fb9ad1dda1120b16663f' 
  AND token = 'jLjojHyJ2bjfrhFgl96njmMzZp3BFCUgZ9Nn9VkR9oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}