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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19a2daba020efa335ef70305821a03e37d2be0b314839f3f4a4214b5ed9af55d' 
  AND token = 'CYBdh/ZcxNdVSE1WTzKrAmltg4p4JhTAxvPf7cei/Ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}